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doi: 10.1177/17474930221135983 54 YaoMRenYJiaYXuJWangYZouKet al
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The proposed mechanisms include upregulation of beta-3 adrenergic receptors in adipose tissue, activation of the cAMP-PKA lipolytic cascade through enhanced catecholamine sensitivity, direct or indirect inhibition of acetyl-CoA carboxylase (ACC) reducing de novo lipogenesis by approximately 43-57% in vitro, and activation of hormone-sensitive lipase (HSL) with increased glycerol release
In addition, there has not been any reports of adverse effects associated with the intake of normal daily requirements of vitamin B12 during lactation
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